Lupus Treatment: What Are the Key Benefits and Risks?
Lupus Treatment
Living with lupus can be tough. The pain, fatigue, and unpredictable flares make everyday life challenging. Many people struggle with joint pain, rashes, and even organ problems. Finding the right lupus treatment can feel confusing and overwhelming, especially with so many medications and possible side effects. If you or someone you love is facing lupus, you might worry about how the medicines will affect your daily life and long-term health. Your family’s understanding and support are crucial in this journey. They can help you manage your medications, keep track of your symptoms, and provide emotional support.

At Brickell Rheumatology Wellness Center, Dr. Bojana Jovanovic takes a personalized approach to lupus care, focusing on tailored treatment, supporting immune health, and developing wellness plans alongside standard medical therapies. Each program addresses the unique needs of the individual and may include lifestyle changes and complementary options. While these therapies can support your treatment, they should be used with, not in place of, prescribed medications. Always consult your doctor before starting new therapies. Patients appreciate Dr. Jovanovic’s thoughtful care and the time she dedicates to understanding their concerns, which fosters a sense of support throughout their journey.
Experience a Personalized Approach to Lupus Treatment
Call Brickell Rheumatology Wellness Center at (305) 928–6001 Today!
(305) 928–6001
What Is Lupus?
Lupus is an autoimmune disease where the immune system mistakenly attacks healthy tissues, causing inflammation, pain, and damage. It can affect the skin, joints, kidneys, heart, and other organs. Since lupus is unpredictable, treatment aims to manage symptoms, prevent flare-ups, and protect organs from long-term damage.
Certain medications may trigger drug-induced lupus, a form that typically resolves after discontinuing the medication. This type differs from systemic lupus erythematosus, which is the more common and severe form and generally has milder symptoms.
The Types of Lupus Treatment Medications
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs like ibuprofen and naproxen help relieve mild lupus symptoms such as joint pain, stiffness, and muscle aches by reducing inflammation. They are often used during flare-ups or when symptoms are less intense. While these medications provide symptom relief, they do not target the underlying immune dysfunction or prevent organ damage. Prolonged use may lead to side effects such as stomach ulcers, kidney problems, or heart issues. To reduce these risks, doctors typically recommend the lowest effective dose for the shortest needed time.
Antimalarial Drugs
Hydroxychloroquine (Plaquenil), a medication approved by the FDA, is often prescribed to manage lupus symptoms such as joint pain, skin rashes, and fatigue. It may also help reduce the frequency of flare-ups. Many individuals tolerate this treatment well and continue using it even after symptoms improve. Possible side effects include nausea, skin discoloration, and retinal damage with long-term use. Rare but serious effects may involve muscle weakness, skin reactions, or allergic responses. If you notice changes in your vision or experience severe symptoms, seek medical attention promptly. Regular eye exams support early detection of potential complications.
Corticosteroids

Corticosteroids like prednisone are powerful anti-inflammatory medications that help manage moderate to severe lupus symptoms, especially when internal organs are involved. They act quickly to reduce swelling and calm the immune response. While effective, they may cause side effects such as weight gain, mood changes, high blood pressure, elevated blood sugar, increased risk of infections, and bone thinning. To reduce long-term risks, doctors typically prescribe the lowest effective dose for the shortest time and gradually taper it as symptoms improve.
Immunosuppressants
Immunosuppressants are often used when lupus affects major organs, such as the kidneys, brain, or heart, to prevent further damage. These medications work by reducing immune system activity to protect healthy tissues. Common options include azathioprine, methotrexate, mycophenolate, cyclophosphamide, cyclosporine, and leflunomide. Because these drugs are stronger than other treatments, they require regular monitoring. Possible side effects may include a higher risk of infections, liver problems, nausea, low blood counts, and an increased risk of cancer. Healthcare providers adjust treatment plans carefully to control symptoms while reducing potential complications.
Biologic Drugs
Biologics are a newer class of targeted therapies, typically used when conventional treatments do not provide sufficient relief. Approved options like belimumab (Benlysta) and anifrolumab (Saphnelo) work by blocking specific proteins in the immune system to reduce inflammation and prevent flare-ups. These medications are typically given by injection or IV and are used for moderate to severe lupus. Other biologics, such as rituximab, may be used in select cases, especially for severe or treatment-resistant lupus. Side effects may include nausea, fever, increased risk of infection, or allergic reactions. Regular monitoring helps track treatment response and manage any complications.
Other Medications
Doctors may prescribe additional medications based on your symptoms. For lupus patients at higher risk of blood clots, blood thinners like warfarin or aspirin may be recommended. Blood pressure medications help support heart and kidney function, while anticonvulsants manage lupus-related seizures, and antibiotics prevent infections. Although these medications don’t directly treat lupus, they play a crucial role in managing related health concerns. A coordinated care approach helps healthcare providers customize treatment to meet each patient’s unique needs.
Tips for Managing Lupus Treatment Side Effects
Take Medicines Exactly as Prescribed
Following your doctor’s instructions helps medications work properly and lowers the risk of side effects. Do not skip doses or change how you take them without consulting your doctor. Consistency enables your treatment to stay effective and safe.
Tell Your Doctor About Any Side Effects
Sharing any side effects with your doctor allows timely adjustments to your treatment. Some issues are easy to manage, while others might need a change in medication. Staying open about your experience helps reduce risks and supports your health.
Get Regular Blood Tests and Eye Exams
Regular monitoring is an essential part of your treatment plan. It helps detect potential side effects early, particularly with medications that can impact your liver, kidneys, or eyes. These tests allow your doctor to track how your body is responding and make sure your treatment remains safe over time.
Eat a Healthy Diet and Exercise
Maintaining a balanced diet and staying active can help lower fatigue, boost your mood, and strengthen your immune system. Eating well and staying active also helps reduce inflammation and manage side effects such as weight gain or elevated blood pressure from certain medications.
Frequently Asked Questions
- Can Lupus Treatment Cure Lupus?
Lupus currently has no cure, but treatment helps manage symptoms and prevent complications. Medications work to reduce inflammation, balance immune responses, and protect vital organs. With a consistent treatment plan and healthy lifestyle, many people live actively and manage lupus effectively. This approach supports a positive and empowered outlook on living with the condition.
- Are There Any Natural Remedies for Lupus Treatment?
Although no natural remedies have been proven to treat lupus, adopting healthy habits, like eating a balanced diet and limiting sun exposure, can support symptom relief. Before using supplements or changing your diet, speak with your doctor to avoid potential risks.
- How Long Will I Need Lupus Treatment?
Lupus treatment typically continues for a lifetime. Lupus is a chronic condition, meaning it doesn’t go away, even if symptoms improve. Continuous treatment helps control inflammation, prevent flare-ups, and protect organs from long-term damage. Your medication plan may change over time depending on your symptoms and disease activity. Regular doctor visits are essential to adjust treatment as needed and enable the most effective, safe management of your condition.
- What Should I Do If I Miss a Dose of My Lupus Treatment?
If you miss a dose of your lupus treatment, take it as soon as you remember. If your next dose is approaching, skip the missed one and stick to your regular schedule. Never take a double dose. Be sure to consult your doctor for personalized guidance.
Comprehensive Lupus Treatment

At Brickell Rheumatology Wellness Center, we help you take control of your health while living with lupus. We know that managing treatment can be overwhelming, but you’re not alone. Dr. Bojana Jovanovic provides dedicated, one-on-one care tailored to your specific needs.
Using a functional medicine approach, we look beyond symptoms to address underlying causes like chronic inflammation and immune system imbalance. Through targeted therapies, lifestyle adjustments, and nutrition-based support, we work to reduce flare-ups and promote long-term wellness.
Lupus treatment is a personal journey — and we’re here to support you every step of the way. We’ll guide you in finding the right medications, managing side effects, and navigating your options with clarity and compassion.
Take the first step today. Schedule your personalized consultation with Dr. Bojana Jovanovic and begin a care plan designed around your health goals.
Discover a Lupus Treatment Plan That Is Tailored to You
Call Brickell Rheumatology Wellness Center at (305) 928–6001 Today!
(305) 928–6001
Brickell Rheumatology Wellness Center
40 SW 13th St Ste #402, Miami, FL 33130, United States
(305) 928–6001
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